Detalhe da pesquisa
1.
Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism.
Mol Cell Proteomics
; 20: 100090, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964423
2.
Development of selective protease inhibitors via engineering of the bait region of human α2-macroglobulin.
J Biol Chem
; 297(1): 100879, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34139236
3.
α2-Macroglobulin-like protein 1 can conjugate and inhibit proteases through their hydroxyl groups, because of an enhanced reactivity of its thiol ester.
J Biol Chem
; 295(49): 16732-16742, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32978260
4.
Mapping Isomeric Peptides Derived from Biopharmaceuticals Using High-Resolution Ion Mobility Mass Spectrometry.
Anal Chem
; 93(49): 16379-16384, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34842410
5.
Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes.
Biochemistry
; 59(51): 4799-4809, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301305
6.
Generic Workflow for Mapping of Complex Disulfide Bonds Using In-Source Reduction and Extracted Ion Chromatograms from Data-Dependent Mass Spectrometry.
Anal Chem
; 90(13): 8202-8210, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29878755
7.
Correction: α2-Macroglobulin-like protein 1 can conjugate and inhibit proteases through their hydroxyl groups, because of an enhanced reactivity of its thiol ester.
J Biol Chem
; 296: 100208, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837737
8.
Complete Mapping of Complex Disulfide Patterns with Closely-Spaced Cysteines by In-Source Reduction and Data-Dependent Mass Spectrometry.
Anal Chem
; 89(11): 5949-5957, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453249
9.
Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry.
Anal Chem
; 88(3): 1585-92, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26695097
10.
Characterization of Insulin Dimers by Top-Down Mass Spectrometry.
J Am Soc Mass Spectrom
; 32(8): 1910-1918, 2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084334
11.
Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320.
J Med Chem
; 64(1): 616-628, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356257
12.
Direct Ultraviolet Laser-Induced Reduction of Disulfide Bonds in Insulin and Vasopressin.
ACS Omega
; 5(14): 7962-7968, 2020 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32309706
13.
Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun
; 11(1): 3746, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32719315
14.
Characterization of Ultraviolet Photoreactions in Therapeutic Peptides by Femtosecond Laser Catalysis and Mass Spectrometry.
ACS Omega
; 4(11): 14517-14525, 2019 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31528806
15.
Electron Transfer Dissociation of All Ions at All Times, MSETD, in a Quadrupole Time-of-Flight (Q-ToF) Mass Spectrometer.
J Am Soc Mass Spectrom
; 28(2): 384-388, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27914015
16.
Author Correction: Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun
; 11(1): 4232, 2020 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244486